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Biological Material Permits

Importing, exporting, or transferring certain biological materials may require permits from federal or state agencies. Outbound Shipping and EH&S Biosafety can help researchers determine permit requirements.

Important Compliance Notice

Failure to comply with hazardous material transportation regulations may result in civil and criminal penalties.

Agencies That May Require Permits

Centers for Disease Control and Prevention (CDC) may regulate: 

  • infectious biological agents
  • infectious substances
  • vectors
  • non-human primate materials
  • bat materials

U.S. Department of Agriculture (USDA) and Animal and Plant Health Inspection Service (APHIS) may regulate:

  • livestock pathogens
  • poultry pathogens
  • plant materials
  • soil
  • genetically engineered organisms
  • veterinary biologics

U.S. Fish & Wildlife Services (FWS) may regulate:

Additional California state agency permits may be required for: 

Researcher Responsibilities

Researchers are responsible for:

  1. Determining whether permits are required.
  2. Coordinating with EH&S Biosafety.
  3. Completing permit applications.
  4. Arranging inspections, if required.
  5. Completing shipping training.
  6. Following all permit conditions.

Permit Application Support

EH&S Biosafety can assist with:

  • determining permit requirements
  • application support
  • agency coordination
  • inspection preparation

Contact EH&S Biosafety

Permit Application Processes

Important Requirements

These permits must be requested under the name of the Principal Investigator. Additional contact information provided in the application should be for laboratory personnel who are responsible for the material. These individuals must be able to answer questions about the shipment from:

  • Customs and Border Protection agents
  • The shipping company
  • The relevant regulatory agency (CDC Import Permit Program, USDA/APHIS, or FWS)

CDC Permits

Use the CDC Import Permit Program website to apply for permits involving infectious biological agents or vectors.

USDA/APHIS Permits

Use the APHIS ePermits system for import, interstate transport, or regulated biological materials.

FWS Permits

Visit the U.S. Fish & Wildlife Service website for wildlife and protected species permits.

Types of Research Permits

This list covers common permits encountered by researchers but is not comprehensive.

This table pairs biological, agricultural, and wildlife permit categories (Column 1) with their corresponding oversight agency (Column 2).
Permit Categories & Form Types Agency
Permit to Import Infectious Biological Agents, Infectious Substances, and Vectors. CDC (Centers for Disease Control)

Plant Protection and Quarantine (PPQ)

  • PPQ 525A: Receive Soil
  • PPQ 526: Move Live Plant Pests/Noxious Weeds
  • PPQ 587/588: Import Plants or Products

Veterinary Services

  • VS 16-3/16-7: Import/Transport Organisms or Vectors
  • VS 17-129: Import Live Animals, Semen, or Embryos
  • APHIS: Veterinary Biological Product Permit

Biotechnology Regulatory Services (BRS)

  • BRS 2000: Movement of Genetically Engineered Organisms
  • BRS Notification: Release of Genetically Engineered Plants
USDA/APHIS (U.S. Dept. of Agriculture)

CITES Permits:

  • Export/Re-Export of Wildlife, Biomedical, or Plant samples
  • Introduction from the Sea
  • Certificate of Scientific Exchange (COSE)

Wildlife & Endangered Species

  • Captive-Bred Wildlife Registration (CBW)
  • Import/Transport of Injurious Wildlife (Lacey Act)
  • Marine Mammal Protection Act/ESA: Research or Rescue
  • Wild Bird Conservation Act: Scientific Research Import
  • Native Endangered & Threatened Species: Recovery & Interstate Commerce
FWS (U.S. Fish & Wildlife Service)

Shipping Materials with a Permit

When shipping permitted materials:

  • Include permit documentation with shipping documents
  • Follow all permit conditions
  • Attach required paperwork to the outside of the package
  • Retain copies for laboratory records

Contact Us

For additional questions or further assistance, please submit a support ticket to Outbound Shipping in Services & Support.