Are all drugs controlled substances (CS)?
No, most drugs are considered pharmaceuticals and are not CS. Examples of drugs that are not CS are Donepezil, Xylazine, and Atropine.
Search the U.S. Drug Enforcement Administration (DEA) List of Controlled Substances (PDF) to see if a drug is considered a CS. One way to tell is to check the label for the letter “C” with a Roman numeral I through V next to it (example: C-IV).
What are schedule numbers and DEA codes?
The federal government assigns each CS a schedule number (I through V) according to its medicinal value, harmfulness, and potential for abuse or addiction. The DEA code is a 4-digit number assigned to each CS. Find schedule numbers and DEA codes at the DEA website.
A higher schedule number indicates the substance has more medicinal value and less potential for abuse or addiction. The letter "N" can also accompany the schedule number, signifying the substance is a non-narcotic. If the DEA website has "N" in the NARC column, the item is a non-narcotic and is denoted by the Roman numeral and an “N” (e.g., IIN). If the DEA website has a "Y" in the NARC column, the item is a narcotic and is denoted so by the absence of the "N" (e.g., II).
The most common CS used in research and their schedule numbers and DEA codes are:
|Pentobarbital (e.g., Nembutal, Fatal Plus)
|Pentobarbital & non-controlled
active ingredients (e.g., B-Euthanasia)
How do I manage my Authorized Personnel?
Use the CSUA Web application to manage your Authorized Personnel. From the My CSUA tab, PIs and CSUA Lab Contacts can add or remove Authorized Personnel, assign privileges, upload PSDS Forms for EH&S approval, and view the approval status of individuals.
See Controlled Substance Use Application, under "Manage Authorized Personnel/ PSDS Forms" for details.
Why do Authorized Personnel applicants need to fill out a Personnel Screening Data Sheet (PSDS)?
Diverting CS from research purposes is one way CS are acquired for illegal recreational use. The PSDS helps restrict CS access to Authorized Personnel, and identify and prohibit access to people with a criminal history of CS diversion or other disqualifications.
The PSDS also documents the individual’s acknowledgement of responsibility to notify the CS Program manager of CS loss or diversion.
Where do I find the PSDS Form?
Select the appropriate PSDS Form (PDF) below:
Read and follow instructions at the top of the form.
What do I do with empty CS bottles?
What are "listed" chemicals?
Listed chemicals, also known as precursor chemicals, are chemicals that may be used to manufacture CS and are regulated by the DEA and California’s Department of Justice. Listed chemicals are controlled in order to prevent the illicit manufacture of CS. Examples of listed chemicals include Thionylchloride Pseudoephedrine and Piperidine.
Why can't I order listed chemicals for my lab directly from the vendor?
Chemical vendors who sell, transfer, or furnish listed chemicals must report to the state or federal government who purchased the chemical and for what purpose. To avoid making this report, chemical vendors increasingly require a CS registration number to purchase List I and California precursor chemicals.
To acquire listed chemicals for nonclinical (research or teaching) purposes, you must have a CSUA from EH&S prior to obtaining listed chemicals. CS orders are placed in the CSUA Web application. A DEA code and schedule number do not apply to these items.
How do I store my listed chemicals?
Store listed chemicals according to their hazard type described on Chemical Storage and Inventory Guidelines. List I and California precursor chemicals must be stored in a locked container within a room that's under human surveillance or locked when not staffed.
Contact the CS Program manager, (858) 534-1362, for a storage consultation prior to requesting listed chemicals.
How do I gain access to the CSUA App?
Only the PI, CS lab contacts, and Department Chair, as named in current or pending CSUAs, can access the CSUA App through the “My Research Safety”
portal. Once you click on “Controlled Substance Use Authorization,” your login will be authenticated through Single Sign On. Individuals will be able to access CSUA information as their role permits.
When does my CSUA expire?
CSUA’s are valid for one year and must be renewed
annually through the CSUA web application
. Renewal reminders are sent to the PI and CSUA Lab Contacts up to 70 days in advance on the first of the month. The expiration date for a CSUA is located online via the CSUA app, under the “My CSUA”
tab, in the right-hand column. Only the PI can renew a CSUA, and renewal extends the CSUA expiration date by a year. CS Lab Contacts can update the contents of a CSUA in preparation for the PI’s renewal. Overdue CSUAs will result in a stoppage of orders and inventory must be relinquished to the CS Program
How do I dispose of CS?
You must return all unused CS to the EH&S Controlled Substances Program for disposal. Use the “My Inventory
” tab in the CSUA web app
to request a disposal
. Request a disposal whenever a research project ends, the CSUA expires, the CS is no longer needed, the PI terminates employment, or the CS expires. For more information, contact the EH&S Controlled Substances Program
What do I do with expired CS?
Any expired inventory must be relinquished to EH&S’s Controlled Substances Program. Contact the CS Program to schedule a time to relinquish the expired CS
What do I do with expired pharmaceuticals (non-CS)?
Pharmaceuticals that are not CS are disposed through the Online Waste Tag Program (OTP). Look at the Pharmaceuticals Disposal
page for more information.
What is Biennial Inventory? Why do I have to do it on a certain date?
The Biennial Inventory
is a date when everyone under that DEA registration reports their inventory. This serves as a snapshot of the inventory on-hand on that date and is the basis for future DEA audits. If you have an approved CSUA, you must participate in the annual or biennial inventory process, even if there are zero controlled substances in stock. The Biennial Inventory is a federal requirement of possessing CS. If Biennial Inventory report is not received, it can result in suspension of the CSUA and stoppage of any orders.
How do I record an error on a log sheet?
If an error is made and needs to be corrected, use a single strike-through to mark out the error, initial, date, and write a short explanation for the change.
How long should I keep my log sheet?
Once an item has been used up or disposed of, submit a copy of the item’s log sheet to EH&S. Retain the original log sheets in the CS logbook for 3 years after the date of item’s complete use or disposal.
Where do I upload a log sheet?
As each item is used up or disposed, review the item’s log sheet for its accuracy. Use the “My Inventory
” tab in the CSUA web app
to upload a copy of the log sheet. Alternatively, you may also submit a copy of the log sheet to the CS Program. The item will be removed from your online inventory list. Retain original log sheets in the CS logbook for 3 years after the item’s complete use or disposal.
Why is there a 21 day wait for California Precursors?
There is a 21-day wait for orders of California Precursors because the CA Department of Justice takes the time to review each order’s proposed usage. Also note that California Precursors must be purchased from a California supplier.
Where do I get training? Is refresher training required?
People working with controlled substances must take the Controlled Substances training
. It is offered as an eCourse through UC Learning Center. Re-take this eCourse every 4 years to meet the refresher requirement.
Who do I contact if I have a question?