The United States Department of Health and Human Services (HHS) and the United States Department of Agriculture (USDA) have identified bacteria, viruses, toxins, rickettsia, and fungi that pose a potential threat to public health or welfare. These organisms, called Select Agents and High Consequence Livestock Pathogens and Toxins, are strictly regulated.

Authorization to use Select Agents:  A Biohazardous Materials Use Authorization (BUA) must be obtained from the UCSD Institutional Biosafety Committee (IBC) prior to receiving or using any Select Agent in isolated form above exempt quantities. The BUA approval process for Select Agents includes registration with the Centers for Disease Control and Prevention (CDC) and/or the Animal and Plant Health Inspection Service (APHIS).

Security requirements:  All individuals with access to Select Agents are required to obtain a security clearance from the Department of Justice. Environment, Health & Safety (EH&S) submits names and fingerprints of all individuals listed in the BUA as working with Select Agents to the Department of Justice.

Every person who enters a laboratory containing Select Agents must either have a security clearance or must be accompanied and monitored by such a person. This includes visitors and employees performing routine cleaning, maintenance, and repairs.

Principal investigators submitting a BUA for approval to use Select Agents must include a security plan that addresses the following elements:

• Physical security
• Cyber security
• Inventory
• Material transfers
• Training
• Suspicious persons and activity reporting
• Provisions for cleaning and maintenance

Physical security requirements are addressed through a risked-based analysis performed by EH&S for each laboratory proposing to use Select Agents.

Theft or loss of Select Agents must be immediately reported to campus police, and EH&S who in turn will report to CDC and/or APHIS.

• Campus Police
  Phone: (858) 534-4357
• Environment, Health & Safety
  Phone: (858) 534-3660

Need an expert? Contact EH&S Biosafety, (858) 822-2493.

Notice: Research safety information, training, and services are intended exclusively for UCSD employees and affiliates.